New diarylheptanoids and a hydroxylated ottelione from Ottelia alismoides

2013004

Hoye, T. R.; Ayyad, S. E. N.; Beckord, H. J.; Brown, S. G. Natural Prod. Commun. 2013, 8, 351–358.

Abstract

Ten new diarylheptanoids (2, 3, 4, 5a-d, 6, 7, and 8) have been isolated from an extract of Ottelia alismoides. The structures of these previously unknown metabolites were determined by NMR spectroscopic analysis. A previously unknown, hydroxylated analog of the known otteliones A and B (1a and 1b)–namely, 3a-hydroxyottelione (13)–was also isolated. The 1H NMR analysis of the Mosher esters of alcohols derived from otteliones A and B (S-17/R-17 and S-20/R-20) are also reported.