Rapid (≤25 °C) Cycloisomerization of Anhydride-tethered Triynes to Benzynes – Origin of a Remarkable Anhydride Linker-induced Rate Enhancement
Sneddon, D. S.; Kevorkian, P. V.; Hoye, T. R. Chem. Sci. 2025, 16, 2898–2906.
An Untethered and Formal Intermolecular Hexadehydro-Diels–Alder Reaction: Alkynylboronates with 2-(1,3-Butadiynyl)pyridines
Kaicharla, T.; Jin, M.; Hoye, T. R. J. Am. Chem. Soc. 2024, 146, 34510–34516.
Alkynes to (Free) Carbenes to Polycyclic Cyclopropanes
Guzman, A. L.; Mann, A. N.; Hoye, T. R. J. Am. Chem. Soc. 2024, 146, 28642–28647.
Relative Rates of Transesterification vis-à-vis Newman’s Rule of Six
Wheeler, A. M. H.; Ahn, S.-C.; Kraemer, N.; Hoye, T. R. J. Org. Chem. 2024, 89, 13485–13490.
Cascade reactions of HDDA-benzynes with tethered cyclohexadienones: strain-driven events originating from ortho-annulated benzocyclobutenes
Chinta, B. S.; Sneddon, D. S.; Hoye, T. R. Chem. Sci. 2024, 15, 8181–8189.
2:1 Adducts Arising from Reactions between Benzynes and 1,3,4-Oxadiazoles
Guzman, A. L.; Kevorkian, P. V.; Hoye, T. R. Org. Lett. 2024, 26, 3834–3839.
Deciphering molecular structures: NMR spectroscopy and quantum mechanical insights of halogenated 4H‐Chromenediones
Martins, L. M. O. S.; Souto, F. T.; Hoye, T. R.; Alvarenga, E. S. Magn. Reson. Chem. 2024, 62, 583–598.
Phosphorane-Promoted C–C Coupling during Aryne Annulations
Kevorkian, P.V.; Sneddon, D.S.; Ritts, C.B.; Hoye, T.R. Angew. Chem. Int. Ed. 2024, e202318774.
Novel Conversions of a Multifunctional, Bio-sourced Lactone Carboxylic Acid
Kaicharla, T.; Lee, S.; Wang, R.; Pehere, A. D.; Xu, S.; Hoye, T. R. Arkivoc 2024, 202312081.
Intramolecular Cyclization of Alkynylheteroaromatic Substrates Bearing a Tethered Cyano Group: A Strategy for Accessing Fused Pyridoheterocycles
Kraemer, N.; Eason, E. M.; Hoye, T. R. J. Org. Chem. 2023, 88, 12716–12726.
Covalent Adduct Formation between β-Lactoglobulin and Flavor Compounds under Thermal Treatments That Mimic Food Pasteurization or Sterilization
Yuan, J.; Anantharamkrishnan, V.; Hoye, T. R.; Reineccius, G. A. J. Agric. Food Chem. 2023, 71, 9481–9489.
Neighboring Group Effects on the Rates of Cleavage of Si–O–Si-Containing Compounds
Gormong, E. A.; Sneddon, D. S.; Reineke, T. M.; Hoye, T. R. J. Org. Chem. 2023, 88, 1988–1995.
The Dual Therapeutic Potential of Ottelione A on Carbon Tetrachloride-induced Hepatic Toxicity in Mice
Zahran, R. F.; EL-sayed, L. M.; Hoye, T. R.; Ayyad, S-E. N. Appl. Biochem. Biotechnol. 2023, 195, 5966–5979.
Examples Showing the Utility of Doping Experiments in 1H NMR Analysis of Mixtures
Kaicharla, T.; Chinta, B.S.; Hoye, T.R. J. Org. Chem. 2022, 87, 5660–5667.
In Situ Allene Formation via Alkyne Tautomerization to Promote [4 + 2]-Cycloadditions with a Pendant Alkyne or Nitrile
Kraemer, N.; Naredla, R.R.; Hoye, T.R. Org. Lett. 2022, 24, 2327–2331.
Defining the Macromolecules of Tomorrow through Synergistic Sustainable Polymer Research
Haque, F.M.; Ishibashi, J.S.A.; Lidston, C.A.L.; Shao, H.; Bates, F.S.; Chang, A.B.; Coates, G.W.; Cramer, C.J.; Dauenhauer, P.J.; Dichtel, W.R.; Ellison, C.J.; Gormong, E.A.; Hamachi, L.S.; Hoye, T.R.; Jin, M.; Kalow, J.A.; Kim, H.J.; Kumar, G.; LaSalle, C.J.; Liffland, S.; Lipinski, B.M.; Pang, Y.; Parveen, R.; Peng, X.; Popowski, Y.; Prebihalo, E.A.; Reddi, Y.; Reineke, T.M.; Sheppard, D.T.; Swartz, J.L.; Tolman, W.B.; Vlaisavljevich, B.; Wissinger, J.; Xu, S.; Hillmyer, M.A. Chem. Rev. 2022, 122, 6322–6373.
Hydrothermal catalysis of waste greases into green gasoline, jet, and diesel biofuels in continuous flow supercritical water
Fedie, R.L.; McNeff, C.V.; McNeff, C.V.; McNeff, L.C.; Greuel, P.G.; Yan, B.; Jenkins, J.A.; Brethorst, J.T.; Frost, G.B.; Hoye, T.R. Biofuels, Bioprod. Bioref. 2022, 16, 349–369.
Synthesis of a novel naphthalenone endoperoxide and structural elucidation by NMR spectroscopy and theoretical calculation
Martins, L.M.O.S.; Santos, J.O.; Hoye, T.R.; Alvarenga, E.S. Magn. Reson. Chem. 2022, 60, 139–147.
Sulfurane [S(IV)]-Mediated Fusion of Benzynes Leads to Helical Dibenzofurans
Ritts, C.B.; Hoye, T.R. J. Am. Chem. Soc. 2021, 143, 13501–13506.
Highlighted in JACS Spotlights 2021, 143, 16875–16876. (DOI: 10.1021/jacs.1c10754)
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Synthesis of Isohexide Diyne Polymers and Hydrogenation to Their Saturated Polyethers
Gormong, E.A.; Reineke, T.M.; Hoye, T.R. ACS Macro Lett. 2021, 10, 1068–1072.
Hexadehydro Diels–Alder (HDDA) Route to Arynes and Related Chemistry
Voss, R.N.; Hoye, T.R. Hexadehydro Diels–Alder (HDDA) Route to Arynes and Related Chemistry. In Modern Aryne Chemistry; Biju, A.T.; Wiley-VCH: Weinheim, Germany, 2021; Chapter 10; pp 407–444.
β-Methyl-δ-valerolactone-containing thermoplastic poly(ester-amide)s: synthesis, mechanical properties, and degradation behavior
Guptill, D. M.; Chinta, B. S.; Kaicharla, T.; Xu, S.; Hoye, T. R. Polym. Chem. 2021, 12, 1310–1316.
Characterization of stereoisomeric 5‐(2‐nitro‐1‐phenylethyl)furan‐2(5H )‐ones by computation of 1H and 13C NMR chemical shifts and electronic circular dichroism spectra
Lopes, D. T.; Hoye, T. R.; Alvarenga, E. S. Magn. Reson. Chem. 2021, 59, 43–51.
Poly(4-ketovalerolactone) from Levulinic Acid: Synthesis and Hydrolytic Degradation
Xu, S.; Wang, Y.; Hoye, T. R. Macromolecules 2020, 53, 4952–4959.
Covalent Adduct Formation Between Flavor Compounds of Various Functional Group Classes and the Model Protein β-Lactoglobulin
Anantharamkrishnan, V.; Hoye, T. R.; Reineccius, G. A. J. Agric. Food Chem. 2020, 68, 6395–6402.
4-Carboalkoxylated Polyvalerolactones from Malic Acid: Tough and Degradable Polyesters
Fahnhorst, G. W.; De Hoe, G. X.; Hillmyer, M. A.; Hoye, T. R. Macromolecules 2020, 53, 3194–3201.
Reactions of HDDA Benzynes with C,N-Diarylimines (ArCH=NAr′)
Arora, S.; Sneddon, D. S.; Hoye, T. R. Eur. J. Org. Chem. 2020, 2379–2383.
Addendum: A guide to small-molecule structure assignment through computation of (¹H and ¹³C) NMR chemical shifts
Willoughby, P.H.; Jansma, M.J.; Hoye, T.R. Nat. Protoc. 2020, 15, 2777.
The aza-hexadehydro-Diels-Alder (aza-HDDA) reaction
Thompson, S. K.; Hoye, T. R. J. Am. Chem. Soc. 2019, 141, 19575–19580.
Reactions of thermally generated benzynes with six-membered N–heteroaromatics: Pathway and product diversity
Arora, S.; Zhang, J.; Pogula, V.; Hoye, T. R. Chem. Sci. 2019, 10, 9069–9076.
Hydrolytically-degradable homo- and copolymers of a strained exocyclic hemiacetal ester
Neitzel, A. E.; Barreda, L.; Trotta, J. T.; Fahnhorst, G. W.; Haversang, T. J.; Hoye, T. R.; Fors, B. P.; Hillmyer, M. A. Polym. Chem. 2019, 10, 4573–4583.
Superabsorbent Poly(isoprenecarboxylate) Hydrogels from Glucose
Fahnhorst, G. W.; Hoye, T. R. ACS Sustainable Chem. Eng. 2019, 7, 7491–7495.
Reactions of Diaziridines with Benzynes Give N‑Arylhydrazones
Arora, S.; Palani, V.; Hoye, T. R. Org. Lett. 2018, 20, 8082–8085.
This manuscript is dedicated in memory of Professor Harold W. Heine, formerly of Bucknell University, and in recognition of his considerable scientific and mentoring legacy, which has so positively impacted so many (including the outgoing Editor-in-Chief of Organic Letters).
Cu(I)-Mediated Bromoalkynylation and Hydroalkynylation Reactions of Unsymmetrical Benzynes: Complementary Modes of Addition
Xiao, X.; Wang, T.; Xu, F.; Hoye, T. R. Angew. Chem. Int. Ed. 2018, 57, 16564–16568.
BF3-Promoted, Carbene-like, C–H Insertion Reactions of Benzynes
Shen, H.; Xiao, X.; Haj, M. K.; Willoughby, P. H.; Hoye, T. R. J. Am. Chem. Soc. 2018, 140, 15616–15620.
Isomerization of Linear to Hyperbranched Polymers: Two Isomeric Lactones Converge via Metastable Isostructural Polyesters to a Highly Branched Analogue
Fahnhorst, G. W.; Stasiw, D. E.; Tolman, W. B.; Hoye, T. R. ACS Macro Lett. 2018, 7, 1144–1148.
Atypical Mode of [3 + 2]-Cycloaddition: Pseudo-1,3-dipole Behavior in Reactions of Electron-Deficient Thioamides with Benzynes
Zhang, J.; Page, A. C. S.; Palani, V.; Chen, J.; Hoye, T. R. Org. Lett. 2018, 20, 5550–5553.
Fatty-acid derivative acts as a sea lamprey migratory pheromone
Li, K.; Brant, C. O.; Huertas, M.; Hessler, E. J.; Mezei, G.; Scott, A. M.; Hoye, T. R.; Li, W. Proc. Natl. Acad. Sci. U.S.A. 2018, 115, 8603–8608.
Unraveling substituent effects on the glass transition temperatures of biorenewable polyesters
Yu, X.; Jia, J.; Xu, S.; Lao, K. U.; Sanford, M. J.; Ramakrishnan, R. K.; Nazarenko, S. I.; Hoye, T. R.; Coates, G. W.; DiStasio R. A. Jr. Nature Commun. 2018, 9, 2880.
The domino hexadehydro-Diels–Alder reaction transforms polyynes to benzynes to naphthynes to anthracynes to tetracynes (and beyond?)
Xiao, X.; Hoye, T. R. Nature Chem. 2018, 10, 838–844.
Highlighted in Synfacts 2018, 14, 1035. (DOI: 10.1055/s-0037-1610940)
and in Chem 2018, 4, 2272–2274. (DOI: 10.1016/j.chempr.2018.09.021)
Benzocyclobutadienes: An unusual mode of access reveals unusual modes of reactivity
Xiao, X.; Woods, B. P.; Xiu, W.; Hoye, T. R. Angew. Chem. Int. Ed. 2018, 57, 9901–9905.
Engineering the Production of Dipicolinic Acid in E. coli
McClintock, M. K.; Fahnhorst, G. W.; Hoye, T. R.; Zhang, K. Metab. Eng. 2018, 48, 208–217.
Trapping of Hexadehydro-Diels–Alder Benzynes with Exocyclic, Conjugated Enals as a Route to Fused Spirocyclic Benzopyran Motifs
Wang, T.; Oswood, C. J.; Hoye, T. R. Syn. Lett. 2017, 28, A-C.
Dedicated with very best wishes to Professor Victor Snieckus on the occasion of his 80th birthday.
Bile Salt-like Dienones Having a Novel Skeleton or a Rare Substitution Pattern Function as Chemical Cues in Adult Sea Lamprey
Li, K.; Scott, A.M.; Brant, C.O.; Fissette, S.D.; Riedy, J.J.; Hoye, T.R.; Li, W. Org. Lett. 2017, 19, 4444–4447.
The Photochemical Hexadehydro-Diels-Alder (hv-HDDA) Reaction
Xu, F.; Xiao, X.; Hoye, T. R. J. Am. Chem. Soc. 2017, 139, 8400–8403.
Highlighted in Synfacts 2017, 13, 809. (DOI: 10.1055/s-0036-1590716)
Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment
Nyongbela, K.D.; Ntie-Kang, F.; Hoye, T.R.; Efange, S.M.N. Nat. Prod. Bioprospect. 2017, 1–13.
Thermoplastic polyurethanes from b-methyl-d-valerolactone-derived amidodiol chain extenders
Guptill, D. M.; Brutman, J. P.; Hoye, T. R. Polymer 2017, 111, 252–257.
The phenol-ene reaction: Biaryl synthesis via trapping reactions between HDDA-generated benzynes and phenolics
Zhang, J.; Niu, D.; Brinker, V. A.; Hoye, T. R. Org. Lett. 2016, 18, 5596–5599.
Poly(isoprenecarboxylates) from glucose via anhydromevalonolactone
Ball-Jones, N. R.; Fahnhorst, G. W.; Hoye, T. R. ACS Macro Lett. 2016, 5, 1128–1131.
Blue-emitting arylalkynyl naphthalene derivatives via a hexadehydro-Diels-Alder (HDDA) cascade reaction
Xu, F.; Hershey, K. W.; Holmes, R. J.; Hoye, T. R. J. Am. Chem. Soc. 2016, 138, 12739–12742.
The hexadehydro-Diels–Alder (HDDA) cycloisomerization reaction proceeds by a stepwise mechanism
Wang, T.; Niu, D.; Hoye, T. R. J. Am. Chem. Soc. 2016, 138, 7832–7835.
Diels-Alder reactions of furans with itaconic anhydride: Overcoming unfavorable thermodynamics
Pehere, A. D.; Xu, S.; Thompson, S. K.; Hillmyer, M. A.; Hoye, T. R. Org. Lett. 2016, 18, 2584–2587.
The pentadehydro-Diels–Alder reaction
Wang, T.; Naredla, R. R.; Thompson, S. K.; Hoye, T. R. Nature 2016, 532, 484–488.
Reactions of HDDA-derived benzynes with sulfides: Mechanism, modes, and three-component reactions
Chen, J.; Palani, V.; Hoye, T. R. J. Am. Chem. Soc. 2016, 138, 4318–4321.
Isolation and characterization of sclerienone C from Scleria striatinux
Nyongbela, K. D.; Makolo, F. L.; Hoye, T. R.; Efange, S. M. Nat. Prod. Commun. 2016, 11, 5–6.
Nanoparticles containing high loads of paclitaxel silicate prodrugs: Formulation, drug release, and anti-cancer efficacy
Han, J.; Michel, A. R.; Lee, H. S.; Kalscheuer, S.; Wohl, A.; Hoye, T. R.; McCormick, A. V.; Panyam, J.; Macosko, C. W. Mol. Pharmaceutics 2015, 12, 4329–4335.
Mechanism of the intramolecular hexadehydro-Diels–Alder reaction
Marell, D. J.; Furan, L. R.; Woods, B. P.; Lei, X.; Bendelsmith, A. J.; Cramer, C. J.; Hoye, T. R.; Kuwata, K. T. J. Org. Chem. 2015, 80, 11744–11754.
Invited contribution to special issue: 50 Years and Counting: The Woodward-Hoffmann Rules in the 21st Century
Competition between classical and hexadehydro-Diels–Alder (HDDA) reactions of HDDA triynes with furan
Luu Nguyen, Q.; Baire, B.; Hoye, T. R. Tetrahedron Lett. 2015, 56, 3265–3267.
We dedicate this Letter to the memory of Harry H. Wasserman, whose amalgamation of scholarship, artistry, and humanity stand as an admirable model for all to emulate.
iso-Petromyroxols: Novel dihydroxylated tetrahydrofuran enantiomers from sea lamprey (Petromyzon marinus)
Li, K.; Brant, C.; Bussy, U.; Pinnamaneni, H.; Patel, H.; Hoye, T. R.; Li, W. Molecules 2015, 20, 5215–5222.
Differential cytotoxic activity of the petroleum ether extract and its furanosesquiterpenoid constituents from Commiphora molmol resin
Ayyad, S.E.N.; Hoye, T. R.; Alarif, W. M.; Al Ahmadi, S. M.; Basaif, S. A.; Ghandourah, M. A.; Badria, F. A. Zeitschrift für Naturforschung C. 2015, 70, 87–92.
New cytotoxic cyclic peroxide acids from Plakortis sp. marine sponge
Hoye, T. R.; Alarif, W. M.; Basaif, S. S.; Abo-Elkarm, M.; Hamann, M. T.; Wahba, A. E.; Ayyad, S. N. ARKIVOC 2015, 164–175.
(+)- and (-)-Petromyroxols: Antipodal tetrahydrofurandiols from larval sea lamprey (Petromyzon marinus l.) that elicit enantioselective olfactory responses
Li, K.; Huertas, M.; Brant, C.; Chung-Davidson, Y-W.; Bussy, U.; Hoye, T. R.; Li, W. Org. Lett. 2015, 17, 286–289.
Mechanism of the reactions of alcohols with o-benzynes
Willoughby, P. H.; Niu, D.; Wang, T.; Haj, M. K.; Cramer, C. J.; Hoye, T. R. J. Am. Chem. Soc. 2014, 136, 13657–13665.
Ultra-high-throughput screening of natural product extracts to identify proapoptotic inhibitors of Bcl-2 family proteins
Hassig, C.A.; Zeng, F.Y.; Kung, P.; Kiankarimi, M.; Kim, S.; Diaz, P.W.; Zhai, D.; Welsh, K.; Morshedian, S.; Su, Y.; O’Keefe, B.; Newman, D.J.; Rusman, Y.; Kaur, H.; Salomon, C.E.; Brown, S.G.; Baire, B.; Michel, A. R.; Hoye, T. R.; Francis, S.; Georg, G.I.; Walters, M.A.; Divlianska, D.B.; Roth, G.P.; Wright, A.E.; Reed, J.C. J. Biomol. Screen. 2014, 19, 1201–1211.
Rates of hexadehydro-Diels–Alder (HDDA) cyclizations: Impact of the linker structure
Woods, B. P.; Baire, B. ; Hoye, T. R. Org. Lett. 2014, 16, 4578–4581.
Sustainable thermoplastic elastomers from terpene-derived monomers
Bolton, J. M.; Hillmyer, M. A.; Hoye, T. R. ACS Macro Lett. 2014, 3, 717–720.
Silicate esters of paclitaxel and docetaxel: synthesis, hydrophobicity, hydrolytic stability, cytotoxicity, and prodrug potential
Wohl, A. R.; Michel, A. R.; Kalscheuer, S.; Macosko, C. W.; Panyam, J.; Hoye, T. R. J. Med. Chem. 2014, 57, 2368–2379.
A guide to small-molecule structure assignment through computation of (1H and 13C) NMR chemical shifts
Willoughby, P. H.; Jansma, M. J.; Hoye, T. R. Nat. Protoc. 2014, 9, 643–660.
Addendum: Nat. Protoc. 2020, 15, 2277. (DOI: 10.1038/s41596-020-0293-9)
Analysis of seven-membered lactones by computational NMR methods: Proton NMR chemical shift data are more discriminating than carbon
Marell, D. J.; Emond, S. J.; Kulshrestha, A.; Hoye, T. R. J. Org. Chem. 2014, 79, 753–758.
Dichlorination of (HDDA-generated) benzynes and a protocol for interrogating the kinetic order of bimolecular aryne trapping reactions
Niu, D.; Wang, T.; Woods, B. P.; Hoye, T. R. Org. Lett. 2014, 16, 254–257.
The aromatic ene reaction
Niu, D.; Hoye, T. R. Nature Chem. 2014, 6, 34–40.
Highlighted in Synfacts 2014, 10, 258. (DOI: 10.1055/s-0033-1340776)
Flash nanoprecipitation: particle structure and stability
Pustulka, K. M.; Wohl, A. R.; Lee, H. S.; Michel, A. R.; Han, J.; Hoye, T. R.; McCormick, A. V.; Panyam, J.; Macosko, C. W. Mol. Pharmaceutics 2013, 10, 4367–4377.
Alkane desaturation by concerted double hydrogen atom transfer to benzyne
Niu, D.; Willoughby, P. H.; Baire, B.; Woods, B. P.; Hoye, T. R. Nature 2013, 501, 531–534.
Total synthesis of (±)-leuconolam: intramolecular allylic silane addition to a maleimide carbonyl group
Izgu, E. C.; Hoye, T. R. Chem. Sci. 2013, 4, 2262–2266
Highlighted in Synfacts 2013, 9, 589. (DOI: 10.1005/s-0033-1338715)
New diarylheptanoids and a hydroxylated ottelione from Ottelia alismoides
Hoye, T. R.; Ayyad, S. E. N.; Beckord, H. J.; Brown, S. G. Natural Prod. Commun. 2013, 8, 351–358.
Polycationic calixarene PTX013, a potent cytotoxic agent against tumors and drug resistant cancer
Dings, R. P. M.; Levine J. I.; Brown, S. G.; Astorgues-Xerri, L.; MacDonald, J. R.; Hoye, T. .R.; Raymond, E.; Mayo, K. H. Invest. New Drugs 2013, 31, 1142–1150.
Synthesis of complex benzenoids via the intermediate generation of o-benzynes through the hexadehydro-Diels-Alder reaction
Baire, B.; Niu, D.; Willoughby, P. H.; Woods, B. P.; Hoye, T. R. Nat. Protoc. 2013, 8, 501–508.
Structure-based optimization of angiostatic agent 6DBF7, an allosteric antagonist of galectin-1
Dings, R. P. M.; Kumar, N.; Miller, M. C.; Loren, M. L.; Rangwala, H.; Hoye, T. R.; Mayo, K. H. J. Pharm. Exp. Ther. 2013, 344, 589–599.
The hexadehydro-Diels–Alder reaction
Hoye, T. R.; Baire, B.; Niu, D.; Willoughby, P. H.; Woods, B. P. Nature 2012, 490, 208–212.
Highlighted in Synfacts 2013, 9, 153. (DOI: 10.1005/s-0033-1318087)
Polyurethanes based on renewable polyols from bioderived lactones
Gurusamy-Thangavelu, S. A.; Emond, S. J.; Kulshrestha, A.; Hillmyer, M. A.; Macosko, C. W.; Tolman, W. B.; Hoye, T. R. Polymer Chemistry 2012, 3, 2941–2948.
Effects of block copolymer properties on nanocarrier protection from in vivo clearance
D'Addio, S. M.; Saad, W.; Ansell, S. M.; Squiers, J. J.; Adamson, D. H.; Herrera-Alonso, M.; Wohl, A. R.; Hoye, T. R.; Macosko, C. W.; Mayer, L. D.; Vauthier, C.; Prud'homme, R. K. J. Control. Release 2012, 162, 208–217.
A simple confined impingement jets mixer for flash nanoprecipitation
Han, J.; Zhu, Z.; Qian, H.; Wohl, A. R.; Beaman, C. J.; Hoye, T. R.; Macosko, C. W. J. Pharm. Sci. 2012, 101, 4018–4023.
Case study of empirical and computational chemical shift analyses: Reassignment of the relative configuration of phomopsichalasin to that of diaporthichalasin
Brown, S. G.; Jansma, M. J.; Hoye, T. R. J. Nat. Prod. 2012, 75, 1326–1331.
Anti-tumor agent calixarene 0118 targets human galectin-1 as an allosteric inhibitor of carbohydrate binding
Dings, R. P. M.; Miller, M.; Nesmelova, I. V.; Astorgues-Xerri, L.; Kumar, N.; Serova, M.; Chen, X.; Raymond, E.; Hoye, T. R.; Mayo, K. H. J. Med. Chem. 2012, 55, 5121-5129.
A concise total synthesis of (±)- and (–)-okilactomycin D
Niu, D.; Hoye, T. R. Org. Lett. 2012, 14, 828–831.
Highlighted in the following editorial: Terpenoid- and shikimate-derived natural product total synthesis: A personal analysis and commentary on the importance of the papers that appear in this virtual issue. Hale, K. J. Org. Lett. 2013, 15, 3181–3198.